The PEX12 Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to PAF-3. This antibody recognizes Human, and Mouse antigen. The PEX12 Antibody (Center) has been validated for the following applications: ELISA, and Western Blot.
Description
Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle